Insulin resistance can make weight loss difficult
Small amounts of insulin are normally produced after eating which the body uses to turn glucose into energy. Insulin resistance is where the the muscles and the liver resist the action of insulin, so the body has to produce higher amounts to keep the blood glucose levels within a normal range. Insulin resistance can significantly affect lipids by increasing triglycerides and LDL ‘bad’ cholesterol, and decreasing HDL ‘good' cholesterol. Insulin resistance can also increase the risk of developing a blood clot, cause inflammatory changes, and increase blood pressure.
Insulin resistance has been associated with cardiovascular disease, hypertension, PCOS, type 2 diabetes, obesity, and fatty liver disease. Some researchers also believe there's a link between insulin resistance and some forms of cancer. The cause of insulin resistance isn’t completely understood - it's thought to be due in part to genetic factors and partly due to lifestyle. Most people with insulin resistance don't have any symptoms and the effects on the body progress over several years. When the body’s insulin production can't keep up, blood sugar increases and over time can progress to diabetes.