Lipids and cholesterol are fat-like substances in your blood. Some are necessary for good health, but when you have a high level of cholesterol in your blood, a lot of it ends up being deposited in the walls of your arteries and other vital organs. Lifestyle choices including diet, exercise and alcohol intake can all influence cholesterol levels and your risk of developing heart disease.

IDL is a transitional lipoprotein that is eventually converted to LDL. Elevated levels of IDL in the blood can contribute to the buildup of plaque in the arteries, just like LDL.

This LDL blood test separates and quantifies all lipoprotein particles including the ‘large’, less atherogenic LDL-1 and LDL-2 and the ‘small’, highly atherogenic LDL-3 to LDL-7. The blood test also measures VLDL and IDL cholesterol linked with type III dyslipidaemia and associated hyperlipoproteinaemias.

Low-density lipoprotein (LDL) can be categorised into subfractions, which range from LDL-1 through to LDL-7 based on their size and density. Among these subfractions, LDL-1 and LDL-2 are thought to be less atherogenic than LDL-3 to LDL-7, meaning they may have a lower tendency to contribute to the development of atherosclerosis. This is due to the fact that LDL-1 and LDL-2 are larger and more buoyant than LDL-3 to LDL-7, which reduces their likelihood of penetrating the arterial wall and contributing to plaque formation.

Elevated homocysteine blood test levels are a risk factor for cardiovascular disease, and may also be elevated in cases of malnutrition or vitamin B12 or folate deficiency.

C-reactive protein (CRP) is a protein made by the liver and secreted into the blood. It is often the first evidence of inflammation or an infection in the body. Its concentration increases in the blood within a few hours after the start of infection or other inflammatory injury.

Blood glucose is generated from carbohydrates and to use this fuel for energy your body needs insulin. With type 2 diabetes the cells either ignore the insulin or the body doesn't produce enough of it. Glucose then builds up leading to problems with the heart, kidneys, eyes, nerves, and blood vessels.

Research indicates that higher quantities of smaller, denser LDL3-7 particles are linked to inflammation and pose a greater risk of causing atherosclerosis compared to fewer, larger and more buoyant LDL1-2 particles. LDL3-7 particles are smaller and denser, and are more likely to permeate the arterial wall and participate in the formation of plaque.

High levels of Lp(a) increase your risk of atherosclerosis and is an inherited genetic condition. The apo B/apo A-I ratio indicates the cholesterol balance between potentially atherogenic (bad) and anti-atherogenic (good) particles.